High Pressure Jacketed Liposome Extruder | Genizer Machinery
Genizer Jacketed Liposome Extruders is compressed air driven, temperature -controlled, from testing to manufacture production of liposome and lipopolyplex for drug and gene delivery. Homogenous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size . The Jacketed Extruder is virtually no dead-volume and is easily cleaned and suitable for sterilization. The Genizer Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein, or gene through track-etched filters with defined pore size. It is relatively gentle, exposing the formulation to moderate pressures up to 3,000 psi at controlled temperatures . The Genizer Jacketed Extruder is easily cleaned and suitable for sterilization, compliance with FDA and GMP sanitary standards in Pharmaceuticals. Unique Benef